The purpose of this research was to investigate the effectiveness of interactive story reading on reading literacy skills of students with hearing impairment. 30 male students (with an average age of 10 years and four months) with severe and profound hearing loss (above 70 decibels) studying in the fourth grade of Bagcheh Ban schools were selected by purposive sampling and randomly in Two experimental and control groups were placed. The subjects of the experimental group received the interactive story-reading program during 10 sessions in the form of small groups; While the subjects of the control group did not participate in the intervention program. Literary and informational text of Perls test (PIRLS) was used to evaluate the reading literacy skills of the subjects. Data analysis was done using SPSS-25 software. The results using multivariate analysis of covariance (MANCOVA) indicate the improvement of reading literacy skills of students with hearing impairment participating in the present study (P<0.001). According to the results of the present study, interactive story reading is an effective intervention in improving the literacy skills of students with hearing impairment.